acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique

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Chemical Name:acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique
CAS No.:75840-06-1
Molecular Formula:C₂₄H₂₇N₅O₄
Molecular Weight:449.509
Hs Code.:

Synonyms:acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique

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Chemical Property of acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique

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Technology Process of acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique

There total 2 articles about acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 75840-07-2
8-Ethyl-5-oxo-2-[4-(4-oxo-4-phenyl-butyl)-piperazin-1-yl]-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester

: 75840-06-1
acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique

Guidance literature:: With sodium carbonate; In ethanol; water;

Reference yield:

: 939-52-6
4-chloro-1-phenylbutan-1-one

: 75840-06-1
acide <(phenyl-4 oxo-4 butyl)-4 piperazinyl-1>-2 ethyl-8 oxo-5 dihydro-5,8 pyrido <2,3-d> pyrimidine-6 carboxylique

Guidance literature:: Multi-step reaction with 2 steps

1: 4.6 g / triethylamine / dimethylformamide / 7 h / 60 °C

2: 67 percent / Na₂CO₃ / ethanol; H₂O

With sodium carbonate; triethylamine; In ethanol; water; N,N-dimethyl-formamide;