(1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol

Base Information

• Chemical Name: (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol
• CAS No.: 1375006-82-8
• Molecular Formula: C₁₈H₁₆N₈O₃
• Molecular Weight: 392.377

Synonyms:(1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol

Chemical Property of (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol

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Technology Process of (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol

There total 7 articles about (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(4-Nitrophenyl)acetylene (937-31-5) + 2,5-bis(azidomethyl)pyridine (1375006-64-6) + propargyl alcohol (107-19-7) → (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol (1375006-82-8)

Guidance literature:

2,5-bis(azidomethyl)pyridine; propargyl alcohol; With copper diacetate; In methanol; dichloromethane; water; at 20 ℃;

(4-Nitrophenyl)acetylene; With sodium L-ascorbate; In methanol; dichloromethane; water; for 12h; chemoselective reaction;

DOI:10.1021/ol300899n

Reference yield: 76.0%

(4-Nitrophenyl)acetylene (937-31-5) + 5-(azidomethyl)-2-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridine (1375006-74-8) → (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol (1375006-82-8)

Guidance literature:

With copper diacetate; sodium L-ascorbate; In methanol; dichloromethane; water; at 20 ℃; for 12h; chemoselective reaction;

DOI:10.1021/ol300899n

Reference yield: 76.0%

→ (1-((5-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol (1375006-82-8)

Guidance literature:

With copper diacetate; sodium L-ascorbate; In water; at 20 ℃; for 12h;

upstream raw materials:

2,5-bis(azidomethyl)pyridine

(4-Nitrophenyl)acetylene

propargyl alcohol

5-(azidomethyl)-2-((4-(4-nitrophenyl)-1H-1,2,3-triazol-1-yl)methyl)pyridine

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