(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

Base Information

Chemical Name:(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine
CAS No.:639784-40-0
Molecular Formula:C₁₈H₁₂F₄N₂S
Molecular Weight:364.366
Hs Code.:

Synonyms:(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

Suppliers and Price of (4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

Chemical Property:

Purity/Quality:

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Technology Process of (4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

There total 5 articles about (4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 639784-21-7
4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YLAMINE

: 639784-40-0
(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

Guidance literature:: With 4-fluorobenzaldehyde; In ethanol;

Reference yield:

: 455-18-5
4-CF₃C₆H₄CN

: 639784-40-0
(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

Guidance literature:: Multi-step reaction with 5 steps

1.1: thioacetamide / DMF (N,N-dimethyl-formamide) / 30.15 h / 70 - 95 °C

2.1: ethyl 2-chloro-3-oxo-butyrate / ethanol / 12 h

2.2: 3 h

3.1: diphenyl phosphoryl azide; triethylamine / tert-butyl alcohol / 2 h

4.1: trifluoroacetic acid / 1 h

5.1: 4-fluorobenzaldehyde / ethanol

With diphenyl phosphoryl azide; 4-fluorobenzaldehyde; thioacetamide; triethylamine; trifluoroacetic acid; ethyl 2-chloro-3-oxo-butyrate; In DMF (N,N-dimethyl-formamide); ethanol; tert-butyl alcohol;

Reference yield:

: 639784-20-6
[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YI]-CARBAMIC acid TERT-BUTYL ester

: 639784-40-0
(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / 1 h

2: 4-fluorobenzaldehyde / ethanol

With 4-fluorobenzaldehyde; trifluoroacetic acid; In ethanol;