3-(Piperidin-3-yl)propanoic acid hydrochloride

Base Information

• Chemical Name: 3-(Piperidin-3-yl)propanoic acid hydrochloride
• CAS No.: 71985-82-5
• Molecular Formula: C₈H₁₅NO₂*ClH
• Molecular Weight: 193.674
• Hs Code.: 2933399090
• European Community (EC) Number: 817-511-7
• Mol file: 71985-82-5.mol

Synonyms:71985-82-5;3-(piperidin-3-yl)propanoic acid hydrochloride;3-(3-Piperidine)propionic acid HCl;3-(3-PIPERIDINE)PROPIONIC ACID HYDROCHLORIDE;3-piperidin-3-ylpropanoic acid;hydrochloride;3-Piperidinepropanoic acid, hydrochloride;SCHEMBL8182632;WCA98582;MFCD03453312;AKOS015847616;SB42722;AS-31093;A9393;CS-0455157;3-(3-Piperidinyl)propanoic acid hydrochloride;EN300-55767;3-[(3R)-3-piperidyl]propanoic acid;3-[(3S)-3-piperidyl]propanoic acid;J-510937;Z839027062

Chemical Property of 3-(Piperidin-3-yl)propanoic acid hydrochloride

Chemical Property:

• PSA: 49.33000
• LogP: 1.98160
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 193.0869564
• Heavy Atom Count: 12
• Complexity: 136

Purity/Quality:

98%min ^*data from raw suppliers

3-(3-Piperidine)propionicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(CNC1)CCC(=O)O.Cl

Technology Process of 3-(Piperidin-3-yl)propanoic acid hydrochloride

There total 2 articles about 3-(Piperidin-3-yl)propanoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

→ 3-(1-(3-(10,11-Dihydrodibenzo[a,d]cyclohepten-5-ylidene)-1-propyl)piperidin-3-yl)propionic acid hydrochloride (219608-67-0) + 3-(3-piperidyl)propionic acid hydrochloride (71985-82-5)

Guidance literature:

Reference yield: 70.7%

trans-3-(3-pyridyl)acrylic acid (19337-97-4,1126-74-5) → 3-(3-piperidyl)propionic acid hydrochloride (71985-82-5)

Guidance literature:

trans-3-(3-pyridyl)acrylic acid; With palladium 10% on activated carbon; hydrogen; acetic acid; under 31029.7 Torr; Autoclave;

With hydrogenchloride; In ethanol; water;

DOI:10.1021/jo200195a

Reference yield:

3-(3-piperidyl)propionic acid hydrochloride (71985-82-5) → 1-Azabicyclo<3.3.1>nonan-2-one (74331-49-0)

Guidance literature:

With di(n-butyl)tin oxide; In toluene; for 16h; Reflux;

DOI:10.1021/jo200195a

upstream raw materials:

trans-3-(3-pyridyl)acrylic acid

Downstream raw materials:

1-Azabicyclo<3.3.1>nonan-2-one

Refernces

• 1、 -. "Tricycle substituted with azaheterocyclic carboxylic acids". . . Retrieved 2008/06/13.