Technology Process of E-Dec-5-ene-2,9-dione
There total 1 articles about E-Dec-5-ene-2,9-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ethene; [2-(1-methylethoxy-κO)phenylmethyl-κC](nitrato-κO,κO′){rel-(2R,5R,7S)-tricyclo[3.3.1.13,7]decane-2,1-diyl[3-(2,4,6-trimethylphenyl)-1-imidazolidinyl-2-ylidene]}ruthenium;
In
tetrahydrofuran;
at 35 ℃;
for 4h;
under 3800.26 Torr;
Sealed tube;
DOI:10.1021/ja4010267
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 96 percent / m-CPBA / CH2Cl2 / 2 h / 0 - 25 °C
2.1: 85 percent / pyridinium p-toluenesulfonate / 5 h
3.1: 92 percent / trimethylsilyl triflate / CH2Cl2 / 1 h / -78 °C
4.1: ozone / CH2Cl2 / -78 °C
4.2: 98 percent / dimethyl sulfide / CH2Cl2
5.1: NaH / dimethylsulfoxide / 0.5 h / 20 °C
5.2: dimethylsulfoxide / 1 h / 20 °C
6.1: acetic acid; water / (S,S)-cobalt(II)-based chiral catalyst / CH2Cl2; acetonitrile / 96 h
7.1: Et3N; DMAP
With
dmap; trimethylsilyl trifluoromethanesulfonate; water; pyridinium p-toluenesulfonate; sodium hydride; ozone; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid;
(S,S)-cobalt(II)-based chiral catalyst;
In
dichloromethane; dimethyl sulfoxide; acetonitrile;
DOI:10.1021/jo026456b
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 96 percent / m-CPBA / CH2Cl2 / 2 h / 0 - 25 °C
2.1: 85 percent / pyridinium p-toluenesulfonate / 5 h
3.1: 92 percent / trimethylsilyl triflate / CH2Cl2 / 1 h / -78 °C
4.1: ozone / CH2Cl2 / -78 °C
4.2: 98 percent / dimethyl sulfide / CH2Cl2
5.1: NaH / dimethylsulfoxide / 0.5 h / 20 °C
5.2: dimethylsulfoxide / 1 h / 20 °C
6.1: acetic acid; water / (R,R)-cobalt(II)-based chiral catalyst / CH2Cl2; acetonitrile / 96 h
7.1: 70 percent / triethylamine; DMAP / CDCl3 / 0.03 h
With
dmap; trimethylsilyl trifluoromethanesulfonate; water; pyridinium p-toluenesulfonate; sodium hydride; ozone; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid;
(R,R)-cobalt(II)-based chiral catalyst;
In
chloroform-d1; dichloromethane; dimethyl sulfoxide; acetonitrile;
DOI:10.1021/jo026456b
