6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine

Base Information

• Chemical Name: 6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine
• CAS No.: 1043569-13-6
• Molecular Formula: C₂₂H₂₅N₅O₅
• Molecular Weight: 439.471
• Mol file: 1043569-13-6.mol

Synonyms:6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine

Chemical Property of 6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine

There total 1 articles about 6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

6-hydroxy-hex-2-ynoic acid methyl ester (123368-72-9) + 8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amine → C22H25N5O5 + C22H25N5O5 + 6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine (1043569-13-6)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In dichloromethane; toluene; at 20 ℃; for 2h;

DOI:10.1016/j.bmc.2008.04.070

Reference yield: 75.0%

6-amino-9-(5-methoxycarbonylpent-4-ynyl)-8-(3,4,5-trimethoxybenzyl)-9H-purine (1043569-13-6) → C21H25N5O4 (1043569-14-7)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; toluene; at 0 ℃; for 1h;

DOI:10.1016/j.bmc.2008.04.070

upstream raw materials:

6-hydroxy-hex-2-ynoic acid methyl ester

Downstream raw materials:

C₂₁H₂₅N₅O₄