C₂₇H₃₄N₄O₂S₂

Base Information

• Chemical Name: C₂₇H₃₄N₄O₂S₂
• CAS No.: 1357456-00-8
• Molecular Formula: C₂₇H₃₄N₄O₂S₂
• Molecular Weight: 510.725
• Mol file: 1357456-00-8.mol

Synonyms:C₂₇H₃₄N₄O₂S₂

Chemical Property of C₂₇H₃₄N₄O₂S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₄N₄O₂S₂

There total 5 articles about C₂₇H₃₄N₄O₂S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H21N3O2S2 (1357456-62-2) + 1(R)-(4-methoxyphenyl)-ethylamine (6298-96-0,22038-86-4,35600-82-9,41851-59-6) → C27H34N4O2S2 (1357456-00-8) + C27H34N4O2S2

Guidance literature:

With acetic acid; In methanol; 1,2-dichloro-ethane; at 20 - 55 ℃; optical yield given as %de;

DOI:10.1016/j.bmcl.2011.11.126

Reference yield:

(2E)-3-(thiophen-3-yl)prop-2-enoate (1357456-75-7) → C27H34N4O2S2 (1357456-00-8) + C27H34N4O2S2

Guidance literature:

Multi-step reaction with 4 steps

1: hydroquinone / toluene / 24 h / 170 °C

2: water; lithium hydroxide / tetrahydrofuran / 2 h / 60 °C

3: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C

4: acetic acid / methanol; 1,2-dichloro-ethane / 20 - 55 °C

With water; benzotriazol-1-ol; acetic acid; N-ethyl-N,N-diisopropylamine; hydroquinone; lithium hydroxide; In tetrahydrofuran; methanol; 1,2-dichloro-ethane; toluene; 1: Diels-Alder reaction;

DOI:10.1016/j.bmcl.2011.11.126

Reference yield:

C17H11F5O3S → C27H34N4O2S2 (1357456-00-8) + C27H34N4O2S2

Guidance literature:

Multi-step reaction with 3 steps

1: water; lithium hydroxide / tetrahydrofuran / 2 h / 60 °C

2: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C

3: acetic acid / methanol; 1,2-dichloro-ethane / 20 - 55 °C

With water; benzotriazol-1-ol; acetic acid; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In tetrahydrofuran; methanol; 1,2-dichloro-ethane;

DOI:10.1016/j.bmcl.2011.11.126

upstream raw materials:

(1S,2S)-4-oxo-2-(thiophene-3-yl)cyclohexanecarboxylic acid

2-(piperazin-1-yl)thiazole hydrochloride

C₁₈H₂₁N₃O₂S₂

1(R)-(4-methoxyphenyl)-ethylamine