4-cyanophenyl chlorothionoformate

Base Information

• Chemical Name: 4-cyanophenyl chlorothionoformate
• CAS No.: 66300-17-2
• Molecular Formula: C₈H₄ClNOS
• Molecular Weight: 197.645
• Mol file: 66300-17-2.mol

Synonyms:4-cyanophenyl chlorothionoformate

Chemical Property of 4-cyanophenyl chlorothionoformate

Chemical Property:

Purity/Quality:

Min98% HPLC ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-cyanophenyl chlorothionoformate

There total 1 articles about 4-cyanophenyl chlorothionoformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

thiophosgene (463-71-8) + 4-cyanophenol (767-00-0) → 4-cyanophenyl chlorothionoformate (66300-17-2)

Guidance literature:

With sodium hydroxide; In chloroform; water; at 0 - 5 ℃; for 1h;

DOI:10.1002/ejoc.200800231

Reference yield: 93.0%

4-cyanophenyl chlorothionoformate (66300-17-2) + N-methylaniline (100-61-8) → O-(4-cyanophenyl) N-methyl-N-phenyl thiocarbamate (91039-08-6)

Guidance literature:

In dichloromethane; for 0.166667h;

DOI:10.1021/jo102467j

Reference yield: 65.0%

4-cyanophenyl chlorothionoformate (66300-17-2) → 4-(chlorodifluoromethoxy)benzonitrile

Guidance literature:

With bromine trifluoride; In trichlorofluoromethane; at 0 ℃;

DOI:10.1002/ejoc.200800231

upstream raw materials:

thiophosgene

4-cyanophenol

Downstream raw materials:

4-cyanophenyl-O,N,N-dimethyl thiocarbamate

[(5-cyano-2-hydroxyphenylthio)-(dimethylmethoxyphosphoranylidene)methyl]dimethylphosphine oxide

4-cyanophenol

4-cyano-N-methyl-N-phenylbenzamide