1-[(E)-3-phenylprop-2-enoxy]-3-(propan-2-ylamino)propan-2-ol

Base Information

Chemical Name:1-[(E)-3-phenylprop-2-enoxy]-3-(propan-2-ylamino)propan-2-ol
CAS No.:105217-58-1
Molecular Formula:C₁₅H₂₃NO₂
Molecular Weight:249.353
Hs Code.:
DSSTox Substance ID:DTXSID70874735
Nikkaji Number:J1.552.469C

Synonyms:105217-58-1;DTXSID70874735;2-PROPANOL, 1-[(1-METHYLETHYL)AMINO]-3-[(3-PHENY

Suppliers and Price of 1-[(E)-3-phenylprop-2-enoxy]-3-(propan-2-ylamino)propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-[(E)-3-phenylprop-2-enoxy]-3-(propan-2-ylamino)propan-2-ol

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:249.172878976
Heavy Atom Count:18
Complexity:223

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)NCC(COCC=CC1=CC=CC=C1)O
Isomeric SMILES:CC(C)NCC(COC/C=C/C1=CC=CC=C1)O

Technology Process of 1-[(E)-3-phenylprop-2-enoxy]-3-(propan-2-ylamino)propan-2-ol

There total 2 articles about 1-[(E)-3-phenylprop-2-enoxy]-3-(propan-2-ylamino)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 474097-67-1
2-<(cinnamyloxy)methyl>oxirane

: 75-31-0
isopropylamine

: 105217-58-1
1-Isopropylamino-3-(3-phenyl-2-propen-1-oxy)-propan-2-ol

Guidance literature:: In ethanol; for 2h; Heating;
DOI:10.1016/0223-5234(88)90138-9

Reference yield:

: 4407-36-7
(2E)-3-phenyl-2-propen-1-ol

: 105217-58-1
1-Isopropylamino-3-(3-phenyl-2-propen-1-oxy)-propan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / 1.) NaOCH₃ / 1.) MeOH, reflux, 1h, 2.) DMF, room temp., 12 h

2: 40 percent / 4 h / 100 °C

With sodium methylate;
DOI:10.1002/ardp.19883211007