methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate

Base Information

• Chemical Name: methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate
• CAS No.: 936484-13-8
• Molecular Formula: C₂₃H₂₇NO₉
• Molecular Weight: 461.469
• Mol file: 936484-13-8.mol

Synonyms:methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate

Chemical Property of methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate

There total 5 articles about methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

C29H33NO12 (936484-08-1) → methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate (936484-13-8)

Guidance literature:

With sodium; In methanol; for 2.5h;

DOI:10.1016/j.carres.2007.01.014

Reference yield:

4-benzyloxycarbonylamido-3,5-dimethylphenol (936484-05-8) → methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate (936484-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / 4 Angstroem MS; AgOTf / CH₂Cl₂ / 3 h / 20 °C

2: 71 percent / Na / methanol / 2.5 h

With 4 Angstroem MS; silver trifluoromethanesulfonate; sodium; In methanol; dichloromethane;

DOI:10.1016/j.carres.2007.01.014

Reference yield:

3,5-dimethyl-4-aminophenol (3096-70-6) → methyl [(4-benzyloxycarbonylamido-3,5-dimethylphenyl) β-D-glucopyranosid]uronate (936484-13-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / NaOAc / H₂O; ethyl acetate; toluene / 0.67 h

2: 57 percent / 4 Angstroem MS; AgOTf / CH₂Cl₂ / 3 h / 20 °C

3: 71 percent / Na / methanol / 2.5 h

With 4 Angstroem MS; sodium acetate; silver trifluoromethanesulfonate; sodium; In methanol; dichloromethane; water; ethyl acetate; toluene;

DOI:10.1016/j.carres.2007.01.014

upstream raw materials:

C₂₉H₃₃NO₁₂

4-benzyloxycarbonylamido-3,5-dimethylphenol

3,5-dimethyl-4-aminophenol

benzyl chloroformate

Downstream raw materials:

C₁₅H₂₁NO₇