dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

Base Information

Chemical Name:dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate
CAS No.:1361968-35-5
Molecular Formula:C₃₆H₂₈F₃N₂O₅P
Molecular Weight:656.598
Hs Code.:

Synonyms:dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

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Technology Process of dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

There total 9 articles about dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 990-91-0
dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate

: 1361967-00-1
SL-2-25

: 1361968-35-5
dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

Guidance literature:: SL-2-25; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h;

dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate; for 0.333333h;
DOI:10.1021/jm201184h

Reference yield: 80.0%

: 1361968-35-5
dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

Guidance literature:

Reference yield:

: 1361968-43-5
1-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)propan-1-ol

: 1361968-35-5
dibenzyl (3-methyl-2-(6-(4-(trifluoromethoxy)phenyl)pyridin-3-yl)quinolin-4-yl) phosphate

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridinium chlorochromate / dichloromethane / 20 °C / Inert atmosphere

2.1: toluene-4-sulfonic acid / butan-1-ol / 24 h / 130 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C

3.2: 0.33 h

With sodium hydride; toluene-4-sulfonic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; mineral oil; butan-1-ol;
DOI:10.1021/jm201184h