C₅₁H₇₁N₇O₁₂Si

Base Information

• Chemical Name: C₅₁H₇₁N₇O₁₂Si
• CAS No.: 186522-59-8
• Molecular Formula: C₅₁H₇₁N₇O₁₂Si
• Molecular Weight: 1002.25
• Mol file: 186522-59-8.mol

Synonyms:C₅₁H₇₁N₇O₁₂Si

Chemical Property of C₅₁H₇₁N₇O₁₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₇₁N₇O₁₂Si

There total 14 articles about C₅₁H₇₁N₇O₁₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-N-benzyloxy-alanine Me Ester (55322-21-9) → C51H71N7O12Si (186522-59-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 1M NaOH / tetrahydrofuran / 0 °C

2: H₂SO₄ / CH₂Cl₂; dioxane

3: 12percent aq. NaHCO₃ / CH₂Cl₂ / 0 °C

4: 93 percent / TFA / CH₂Cl₂

5: BOP-Cl, Et₃N / CH₂Cl₂ / -20 - 0 °C

6: Et₂NH / acetonitrile

With sodium hydroxide; sulfuric acid; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydrogencarbonate; diethylamine; triethylamine; trifluoroacetic acid; In tetrahydrofuran; 1,4-dioxane; dichloromethane; acetonitrile;

DOI:10.1016/S0040-4039(00)78375-4

Reference yield:

N-Benzyloxy-L-alanin-tert.-butylester (55322-23-1) → C51H71N7O12Si (186522-59-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 12percent aq. NaHCO₃ / CH₂Cl₂ / 0 °C

2: 93 percent / TFA / CH₂Cl₂

3: BOP-Cl, Et₃N / CH₂Cl₂ / -20 - 0 °C

4: Et₂NH / acetonitrile

With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydrogencarbonate; diethylamine; triethylamine; trifluoroacetic acid; In dichloromethane; acetonitrile;

DOI:10.1016/S0040-4039(00)78375-4

Reference yield:

(S)-N-benzyloxy-alanine (54837-16-0) → C51H71N7O12Si (186522-59-8)

Guidance literature:

Multi-step reaction with 5 steps

1: H₂SO₄ / CH₂Cl₂; dioxane

2: 12percent aq. NaHCO₃ / CH₂Cl₂ / 0 °C

3: 93 percent / TFA / CH₂Cl₂

4: BOP-Cl, Et₃N / CH₂Cl₂ / -20 - 0 °C

5: Et₂NH / acetonitrile

With sulfuric acid; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; sodium hydrogencarbonate; diethylamine; triethylamine; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; acetonitrile;

DOI:10.1016/S0040-4039(00)78375-4

upstream raw materials:

N-Benzyloxy-L-alanin-tert.-butylester

(S)-N-benzyloxy-alanine Me Ester

(S)-N-benzyloxy-alanine

D-(N^α-Fmoc,N^δ-Cbz)-Piz-Cl