(1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Base Information

Chemical Name:(1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol
CAS No.:853786-21-7
Molecular Formula:C₁₃H₂₀O₇
Molecular Weight:288.298
Hs Code.:

Synonyms:(1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Suppliers and Price of (1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

There total 4 articles about (1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 179122-39-5
(E)-3-(3,5-dimethoxy-4-(methoxymethoxy)phenyl)prop-2-en-1-ol

: 853786-21-7
(1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Guidance literature:: With methanesulfonamide; 1,4-bis(9-O-dihydroquinidine)phthalazine; In water; tert-butyl alcohol; at 0 ℃; for 48h;
DOI:10.1016/j.tetasy.2005.02.035

Reference yield:

: 853786-20-6
ethyl (E)-3,5-dimethoxy-4-(methoxymethoxy)-cinnamate

: 853786-21-7
(1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / DIBAL-H / toluene; hexane / -10 °C

2: 80 percent / AD mix-β; methanesulfonamide / 2-methyl-propan-2-ol; H2O / 48 h / 0 °C

With methanesulfonamide; diisobutylaluminium hydride; 1,4-bis(9-O-dihydroquinidine)phthalazine; In hexane; water; toluene; tert-butyl alcohol; 2: Sharpless asymmetric dihydroxylation;
DOI:10.1016/j.tetasy.2005.02.035

Reference yield:

: 55211-66-0
3,5-dimethoxy-4-(methoxymethoxy)benzaldehyde

: 853786-21-7
(1R,2R)-1-(3',5'-dimethoxy-4'-methoxymethoxyphenyl)-2,3-dihydroxypropanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / tetrahydrofuran / 0 - 18 °C

1.2: 83 percent / tetrahydrofuran / 4 h / 18 °C

2.1: 81 percent / DIBAL-H / toluene; hexane / -10 °C

3.1: 80 percent / AD mix-β; methanesulfonamide / 2-methyl-propan-2-ol; H2O / 48 h / 0 °C

With methanesulfonamide; sodium hydride; diisobutylaluminium hydride; 1,4-bis(9-O-dihydroquinidine)phthalazine; In tetrahydrofuran; hexane; water; toluene; tert-butyl alcohol; 1.2: Horner-Wadsworth-Emmons / 3.1: Sharpless asymmetric dihydroxylation;
DOI:10.1016/j.tetasy.2005.02.035