phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside

Base Information

• Chemical Name: phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside
• CAS No.: 910041-16-6
• Molecular Formula: C₂₇H₃₄O₆S
• Molecular Weight: 486.629
• Mol file: 910041-16-6.mol

Synonyms:phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside

Chemical Property of phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside

There total 1 articles about phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

phenyl 2-O-benzyl-1-thio-α-L-rhamnopyranoside (849938-16-5) + butanoic acid anhydride (106-31-0) → phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside (910041-16-6)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.bmc.2006.05.009

Reference yield: 96.0%

phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside (910041-16-6) → 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranosyl bromide (910041-17-7)

Guidance literature:

With bromine; In dichloromethane; at 0 ℃; for 0.333333h;

DOI:10.1016/j.bmc.2006.05.009

Reference yield:

phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside (910041-16-6) → kaempferol 3-O-(3'',4''-di-O-butyryl-α-L-rhamnopyranoside)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / bromine / CH₂Cl₂ / 0.33 h / 0 °C

2: Ag₂O; molecular sieves 4 Angstroem / CH₂Cl₂ / 4 h / 20 °C

3: 0.09 g / H₂ / Pd(OH)2/C / tetrahydrofuran; methanol / 2 h

With 4 A molecular sieve; hydrogen; bromine; silver(l) oxide; palladium dihydroxide; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1016/j.bmc.2006.05.009

upstream raw materials:

phenyl 2-O-benzyl-1-thio-α-L-rhamnopyranoside

butanoic acid anhydride

Downstream raw materials:

3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranosyl bromide