Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

Base Information

• Chemical Name: Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester
• CAS No.: 80179-08-4
• Molecular Formula: C₁₃H₂₂O₃
• Molecular Weight: 226.316
• Mol file: 80179-08-4.mol

Synonyms:Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

Chemical Property of Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

There total 1 articles about Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

(+)-(1R,3S,1'R)-3-acetoxymethyl-1-(1',2'-epoxyethyl)-1,2,2-trimethylcyclopentane (75100-54-8,75110-94-0) → Acetic acid (1S,3R,4R)-3-fluoro-4-hydroxymethyl-2,2,3-trimethyl-cyclohexylmethyl ester (80179-09-5) + Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester (80179-08-4)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; for 4h;

Reference yield: 98.0%

acetic anhydride (108-24-7) + Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester (80179-08-4) → Acetic acid (1S,4S)-4-acetoxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester (80179-10-8)

Guidance literature:

With pyridine; for 1h; Ambient temperature;

Reference yield: 70.0%

Acetic acid (1S,4S)-4-hydroxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester (80179-08-4) → Acetic acid (1S,4S)-4-bromomethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester (73616-73-6,76231-57-7)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In diethyl ether; for 4h; Ambient temperature;

upstream raw materials:

(+)-(1R,3S,1'R)-3-acetoxymethyl-1-(1',2'-epoxyethyl)-1,2,2-trimethylcyclopentane

Downstream raw materials:

Acetic acid (1S,4S)-4-acetoxymethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

Acetic acid (1S,4S)-4-bromomethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

((1S,4S)-2,2,4-Trimethyl-3-methylene-cyclohexyl)-methanol

(3S,6S)-6-Methoxymethyl-1,1,3-trimethyl-2-methylene-cyclohexane