Technology Process of 2,3,2',3'-tetra-O-(p-methoxybenzyl)-4,6;4',6'-di-O-(p-methoxybenzylidene)-α,α-D-trehalose
There total 3 articles about 2,3,2',3'-tetra-O-(p-methoxybenzyl)-4,6;4',6'-di-O-(p-methoxybenzylidene)-α,α-D-trehalose which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4,6;4′,6′-di-O-(p-methoxybenzylidene)-α,α-D-trehalose;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 2 ℃;
for 0.333333h;
Inert atmosphere;
p-methoxybenzyl chloride;
With
tetra-(n-butyl)ammonium iodide;
In
N,N-dimethyl-formamide; mineral oil;
at 100 ℃;
Cooling with ice;
DOI:10.1039/c3ob41389f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: camphor-10-sulfonic acid / N,N-dimethyl-formamide / 5 h / 60 °C / 105.01 Torr / pH Ca. 1 / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 2 °C / Inert atmosphere
2.2: 100 °C / Cooling with ice
With
camphor-10-sulfonic acid; sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
DOI:10.1039/c3ob41389f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: camphor-10-sulfonic acid / N,N-dimethyl-formamide / 5 h / 60 °C / 105.01 Torr / pH Ca. 1 / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 2 °C / Inert atmosphere
2.2: 100 °C / Cooling with ice
With
camphor-10-sulfonic acid; sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
DOI:10.1039/c3ob41389f
