2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile

Base Information

Chemical Name:2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS No.:65242-27-5
Molecular Formula:C10H9 Cl N2
Molecular Weight:192.648
Hs Code.:2933499090
European Community (EC) Number:851-365-5
DSSTox Substance ID:DTXSID80396312
Nikkaji Number:J2.742.400G
Wikidata:Q82196958
ChEMBL ID:CHEMBL1385133
Mol file:65242-27-5.mol

Synonyms:2-chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile;65242-27-5;2-chloro-5,6,7,8-tetrahydro-3-quinolinecarbonitrile;MLS000697960;SCHEMBL5624979;CHEMBL1385133;DTXSID80396312;HMS2577E04;MFCD02026185;STK000140;AKOS000119311;AT32339;SMR000228598;EN300-25441;2-chloro-3-cyano-5,6,7,8-tetrahydroquinoline;A867702;AN-329/14296042;SR-01000493604;12R-1240;SR-01000493604-1;2-chloro-5,6,7,8-tetrahydro-quinoline-3-carbonitrile;Z57200734;F0918-2415

Suppliers and Price of 2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile
50mg
$ 45.00

TRC
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile
100mg
$ 90.00

Matrix Scientific
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile 95%+
500mg
$ 172.00

Matrix Scientific
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile 95%+
100mg
$ 72.00

Matrix Scientific
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile 95%+
2.500g
$ 571.00

Crysdot
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile 95+%
1g
$ 432.00

Chemenu
2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile 95%
1g
$ 408.00

ChemBridge Corporation
2-chloro-5,6,7,8-tetrahydro-3-quinolinecarbonitrile 95%
5 g
$ 297.00

Aronis compounds
2-chloro-5,6,7,8-tetrahydro-3-quinolinecarbonitrile
20mg
$ 30.00

American Custom Chemicals Corporation
2-CHLORO-5,6,7,8-TETRAHYDROQUINOLINE-3-CARBONITRILE 95.00%
10G
$ 2079.00

Total 12 raw suppliers

Chemical Property of 2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile

Chemical Property:

Vapor Pressure:0.000273mmHg at 25°C
Refractive Index:1.585
Boiling Point:322.8°C at 760 mmHg
Flash Point:149°C
PSA：36.68000
Density:1.28g/cm³
LogP:2.48548
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:192.0454260
Heavy Atom Count:13
Complexity:232

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2=NC(=C(C=C2C1)C#N)Cl

Technology Process of 2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile

There total 3 articles about 2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.6%

: 4241-13-8
2-oxo-1,2,5,6,7,8-hexahydro-3-quinoline-3-carbonitrile

: 65242-27-5
2-chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile

Guidance literature:: With trichlorophosphate; for 8h; Heating;
DOI:10.1007/s11094-015-1334-5

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 65242-27-5
2-chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: alkyl formate / 24 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere; Reflux

2.1: trichlorophosphate / 25 h / 20 °C / Inert atmosphere; Reflux

With trichlorophosphate;
DOI:10.1055/s-0036-1588619