(S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

Base Information

Chemical Name:(S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine
CAS No.:148694-56-8
Molecular Formula:C₁₆H₁₆ClFN₄OS
Molecular Weight:366.847
Hs Code.:

Synonyms:(S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

Suppliers and Price of (S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

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Technology Process of (S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

There total 3 articles about (S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 6-Chloro-9-[(S)-1-fluoromethyl-2-(toluene-4-sulfinyl)-ethoxymethyl]-9H-purine

: 148694-56-8
(S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

: (2S)-6-chloro-9-<(1,3-difluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

Guidance literature:: With diethylamino-sulfur trifluoride; antimony(III) chloride; In dichloromethane; for 3h; Ambient temperature;

Reference yield:

: 114107-10-7
(S)-3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propanol

: 148694-56-8
(S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / HCl (gas) / CH₂Cl₂ / 4 h / 0 °C

2: 1.) ammonium sulphate, hexamethyldisilazane, 2.) mercury(II) cyanide / 1.) reflux, 3 h, 2.) benzene, reflux, 3 h

With hydrogenchloride; ammonium sulfate; mercury(II) cyanide; 1,1,1,3,3,3-hexamethyl-disilazane; In dichloromethane;

Reference yield:

: 148694-52-4
chloromethyl (S)-<3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propyl> ether

: 87-42-3
6-chloropurine

: 148694-56-8
(S)-6-chloro-9-<(3-fluoro-1-<(4-methylphenyl)sulphenyl>-2-propoxy)methyl>purine

Guidance literature:: With ammonium sulfate; mercury(II) cyanide; 1,1,1,3,3,3-hexamethyl-disilazane; Yield given. Multistep reaction; 1.) reflux, 3 h, 2.) benzene, reflux, 3 h;