(2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide

Base Information

Chemical Name:(2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide
CAS No.:1234315-14-0
Molecular Formula:C₁₈H₂₄F₃N₃O₂
Molecular Weight:371.403
Hs Code.:

Synonyms:(2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide

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Technology Process of (2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide

There total 1 articles about (2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1234318-38-7
(2S,4R)-4-hydroxy-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide hydrochloride

: 50488-42-1
2-bromo-5-(trifluoromethyl)pyridine

: 1234315-14-0
(2S,4R)-4-hydroxy-1-(5-trifluoromethyl-pyridin-2-yl)-pyrrolidine-2-carboxylic acid cyclohexylmethyl-amide

Guidance literature:: With copper(l) iodide; tetraethylammonium bromide; potassium carbonate; triethylamine; dichlorobis(tri-O-tolylphosphine)palladium; In N,N-dimethyl-formamide; at 100 ℃; for 22h; Inert atmosphere;