dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester

Base Information

• Chemical Name: dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester
• CAS No.: 917105-55-6
• Molecular Formula: C₂₄H₂₈Cl₂N₂O₄S₂
• Molecular Weight: 543.535
• Mol file: 917105-55-6.mol

Synonyms:dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester

Chemical Property of dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester

There total 3 articles about dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

allyl-(6-chloro-pyridin-2-yl)-carbamic acid tert-butyl ester (917105-34-1) + O-ethyl S-2-(4-chlorophenyl)-2-oxoethyl carbonodithioate (91193-23-6) → dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester (917105-55-6)

Guidance literature:

With dilauryl peroxide; In 1,2-dichloro-ethane; Heating;

DOI:10.1039/b609021d

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester (917105-55-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / NaHMDS / tetrahydrofuran / 1 h / 20 °C

2: 79 percent / lauroyl peroxide / 1,2-dichloro-ethane / Heating

With dilauryl peroxide; sodium hexamethyldisilazane; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1039/b609021d

Reference yield:

allyl(6-chloropyridin-2-yl)amine (791095-96-0) → dithiocarbonic acid [1-{[tert-butoxycarbonyl-(6-chloro-pyridin-2-yl)-amino]-methyl}-4-(4-chloro-phenyl)-4-oxo-butyl] ester ethyl ester (917105-55-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / NaHMDS / tetrahydrofuran / 1 h / 20 °C

2: 79 percent / lauroyl peroxide / 1,2-dichloro-ethane / Heating

With dilauryl peroxide; sodium hexamethyldisilazane; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1039/b609021d

upstream raw materials:

allyl-(6-chloro-pyridin-2-yl)-carbamic acid tert-butyl ester

O-ethyl S-2-(4-chlorophenyl)-2-oxoethyl carbonodithioate

di-tert-butyl dicarbonate

allyl(6-chloropyridin-2-yl)amine