4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Base Information

Chemical Name:4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine
CAS No.:78451-69-1
Molecular Formula:C₁₄H₁₄ClN₅O
Molecular Weight:303.751
Hs Code.:

Synonyms:4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Suppliers and Price of 4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

There total 4 articles about 4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 51022-73-2
4-(3-chloro-phenyl)-1,3-dimethyl-1,6,7,8-tetrahydro-pyrazolo[3,4-e][1,4]diazepine

: 78451-69-1
4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Guidance literature:: With sodium nitrite; In acetic acid; for 1h; Ambient temperature;
DOI:10.1021/jm00140a013

Reference yield:

: 618-46-2
m-Chlorobenzoyl chloride

: 78451-69-1
4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Guidance literature:: Multi-step reaction with 4 steps

1: 68 percent / Ca(OH)2 / dioxane / 1.5 h / Heating

2: 81 percent / POCl₃ / 6 h / Heating

3: 50 percent / 20 h / Heating

4: 28 percent / sodium nitrite / acetic acid / 1 h / Ambient temperature

With calcium hydroxide; sodium nitrite; trichlorophosphate; In 1,4-dioxane; acetic acid;
DOI:10.1021/jm00140a013

Reference yield:

: 58011-00-0
(1,3-dimethyl-5-hydroxy-1H-pyrazol-4-yl)(3-chlorophenyl)methanone

: 78451-69-1
4-(3-chlorophenyl)-1,6,7,8-tetrahydro-1,3-dimethyl-8-nitrosopyrazolo[3,4-e][1,4]diazepine

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / POCl₃ / 6 h / Heating

2: 50 percent / 20 h / Heating

3: 28 percent / sodium nitrite / acetic acid / 1 h / Ambient temperature

With sodium nitrite; trichlorophosphate; In acetic acid;
DOI:10.1021/jm00140a013