2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate

Base Information

• Chemical Name: 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate
• CAS No.: 1079152-19-4
• Molecular Formula: C₁₉H₂₀F₃NO₇S
• Molecular Weight: 463.432
• Mol file: 1079152-19-4.mol

Synonyms:2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate

Chemical Property of 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate

There total 1 articles about 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2,2,2-trifluoro-N-phenyl-acetimidoyl chloride (61881-19-4) + 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranose (74006-96-5) → 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate (1079152-19-4)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 1h;

DOI:10.1002/ejoc.200800503

Reference yield: 70.0%

methyl 2,3,4-tri-O-benzoylglucopyranoside (34234-44-1) + 2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranosyl N-phenyl trifluoroacetimidate (1079152-19-4) → methyl 2,3,4-tri-O-acetyl-α-L-arabinopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-glucopyranoside (1079152-29-6)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 0 - 20 ℃; for 2h; stereoselective reaction; Molecular sieve;

DOI:10.1002/ejoc.200800503

upstream raw materials:

2,2,2-trifluoro-N-phenyl-acetimidoyl chloride

2,3,4-tri-O-acetyl-1-thio-α-L-arabinopyranose

Downstream raw materials:

methyl 2,3,4-tri-O-acetyl-α-L-arabinopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-α-D-glucopyranoside