Technology Process of C28H35N5O5
There total 4 articles about C28H35N5O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C21H22N4O3;
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.5h;
2-(tert-butoxycarbonylamino)ethyl bromide;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 15h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium carbonate; XPhos / tris-(dibenzylideneacetone)dipalladium(0) / tert-butyl alcohol / 80 °C
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C
2.2: 15 h / 20 °C
With
potassium carbonate; caesium carbonate; XPhos;
tris-(dibenzylideneacetone)dipalladium(0);
In
N,N-dimethyl-formamide; tert-butyl alcohol;
1.1: Buchwald-Hartwig Pd catalyzed aryl C-N formation;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogen / platinum on carbon / thiophene; methanol; di-isopropyl ether / 16 h
2.1: potassium carbonate; XPhos / tris-(dibenzylideneacetone)dipalladium(0) / tert-butyl alcohol / 80 °C
3.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C
3.2: 15 h / 20 °C
With
hydrogen; potassium carbonate; caesium carbonate; XPhos;
tris-(dibenzylideneacetone)dipalladium(0); platinum on carbon;
In
thiophene; methanol; di-isopropyl ether; N,N-dimethyl-formamide; tert-butyl alcohol;
2.1: Buchwald-Hartwig Pd catalyzed aryl C-N formation;