Methyl 2-amino-2-phenylbutanoate

Base Information

Chemical Name:Methyl 2-amino-2-phenylbutanoate
CAS No.:76142-47-7
Molecular Formula:C₁₁H₁₅NO₂
Molecular Weight:193.246
Hs Code.:
European Community (EC) Number:881-519-7
Nikkaji Number:J89.679I

Synonyms:methyl 2-amino-2-phenylbutanoate;76142-47-7;methyl2-amino-2-phenylbutanoate;MFCD12151671;AKOS005362685;BS-12231;CS-0295765;EN300-71965;Z477335874

Suppliers and Price of Methyl 2-amino-2-phenylbutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Methyl 2-amino-2-phenylbutanoate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:200

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CC=CC=C1)(C(=O)OC)N

Technology Process of Methyl 2-amino-2-phenylbutanoate

There total 4 articles about Methyl 2-amino-2-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: (E)-methyl 2-(2-(2-methoxy-2-oxo-1-phenylethylidene)hydrazinyl)-2-phenylbutanoate

: 76142-47-7
methyl 2-amino-2-phenylbutanoate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 80 ℃; for 15h; under 8274.59 Torr; Sealed tube;
DOI:10.1021/acs.orglett.5b01836

Reference yield:

: 22979-35-7
Methyl phenyldiazoacetate

: 76142-47-7
methyl 2-amino-2-phenylbutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: dirhodium tetraacetate / toluene / 20 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 15 h / 80 °C / 8274.59 Torr / Sealed tube

With dirhodium tetraacetate; palladium 10% on activated carbon; hydrogen; In methanol; toluene;
DOI:10.1021/acs.orglett.5b01836