ethyl-3->-E-propenoate

Base Information

Chemical Name:ethyl-3->-E-propenoate
CAS No.:223526-37-2
Molecular Formula:C₂₅H₃₆N₂O₇
Molecular Weight:476.57
Hs Code.:

ethyl-3-<Boc-L-<(N-2,4-dimethoxybenzyl)-(S)-Pyrrol-Ala>>-E-propenoate

Synonyms:ethyl-3->-E-propenoate

Suppliers and Price of ethyl-3->-E-propenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl-3->-E-propenoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl-3->-E-propenoate

There total 7 articles about ethyl-3->-E-propenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136904-77-3
(4S)-4-(2-methoxycarbonylethyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester

: 223526-37-2
ethyl-3->-E-propenoate

Guidance literature:: Multi-step reaction with 7 steps

1: aq. 4.0 M NaOH / methanol / 3.5 h / 23 °C

2: 1.) pivaloyl chloride, Et₃N, 2.) LiCl / 1.) THF, 0 deg C, 3.5 h, 2.) THF, 23 deg C, 19 h

3: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 20 min, 2.) THF, a) -78 deg C, 3 h, b) -45 deg C, 2 h

4: 1.) O₃, CH₃OH, 2.) Me₂S / 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂, a) -78 deg C, 3.5 h, b) 0 deg C, 1 h

5: 1.) NaOAc, NaCNBH₃, 2.) TsOH*H₂O / 1.) THF, EtOH, 23 deg C, 20 h, 2.) CH₃OH, 50 deg C, 2.5 h

6: 1.) oxalyl chloride, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 20 min, 2.) CH₂Cl₂, -78 deg C, 1.5 h

7: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 20 min, 2.) THF, -78 deg C, 45 min

With methanol; sodium hydroxide; oxalyl dichloride; dimethylsulfide; sodium acetate; sodium hexamethyldisilazane; pivaloyl chloride; sodium cyanoborohydride; toluene-4-sulfonic acid; ozone; dimethyl sulfoxide; triethylamine; lithium chloride; In methanol;
DOI:10.1021/jm9805384

Reference yield:

: 223526-25-8
(4S)-4-(2'-carboxyethyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester

: 223526-37-2
ethyl-3->-E-propenoate

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) pivaloyl chloride, Et₃N, 2.) LiCl / 1.) THF, 0 deg C, 3.5 h, 2.) THF, 23 deg C, 19 h

2: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 20 min, 2.) THF, a) -78 deg C, 3 h, b) -45 deg C, 2 h

3: 1.) O₃, CH₃OH, 2.) Me₂S / 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂, a) -78 deg C, 3.5 h, b) 0 deg C, 1 h

4: 1.) NaOAc, NaCNBH₃, 2.) TsOH*H₂O / 1.) THF, EtOH, 23 deg C, 20 h, 2.) CH₃OH, 50 deg C, 2.5 h

5: 1.) oxalyl chloride, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 20 min, 2.) CH₂Cl₂, -78 deg C, 1.5 h

6: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 20 min, 2.) THF, -78 deg C, 45 min

With methanol; oxalyl dichloride; dimethylsulfide; sodium acetate; sodium hexamethyldisilazane; pivaloyl chloride; sodium cyanoborohydride; toluene-4-sulfonic acid; ozone; dimethyl sulfoxide; triethylamine; lithium chloride;
DOI:10.1021/jm9805384

Reference yield:

: 223526-27-0
(4S,4''S)-4-<3'-(4''-benzyl-2''-oxo-oxazolidin-3''-yl)-3'-oxo-propyl>-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester

: 223526-37-2
ethyl-3->-E-propenoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 20 min, 2.) THF, a) -78 deg C, 3 h, b) -45 deg C, 2 h

2: 1.) O₃, CH₃OH, 2.) Me₂S / 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂, a) -78 deg C, 3.5 h, b) 0 deg C, 1 h

3: 1.) NaOAc, NaCNBH₃, 2.) TsOH*H₂O / 1.) THF, EtOH, 23 deg C, 20 h, 2.) CH₃OH, 50 deg C, 2.5 h

4: 1.) oxalyl chloride, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 20 min, 2.) CH₂Cl₂, -78 deg C, 1.5 h

5: 1.) sodium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 20 min, 2.) THF, -78 deg C, 45 min

With methanol; oxalyl dichloride; dimethylsulfide; sodium acetate; sodium hexamethyldisilazane; sodium cyanoborohydride; toluene-4-sulfonic acid; ozone; dimethyl sulfoxide; triethylamine;
DOI:10.1021/jm9805384