(2R,3R)-(+)-2,3-BUTANEDIOL DI-P-TOSYLATE, 99

Base Information

• Chemical Name: (2R,3R)-(+)-2,3-BUTANEDIOL DI-P-TOSYLATE, 99
• CAS No.: 64896-27-1
• Molecular Formula: C18H22 O6 S2
• Molecular Weight: 398.501
• Hs Code.: 2905199090
• Mol file: 64896-27-1.mol

Synonyms:2,3-Butanediol,bis(4-methylbenzenesulfonate), [R-(R*,R*)]- (9CI)

Chemical Property of (2R,3R)-(+)-2,3-BUTANEDIOL DI-P-TOSYLATE, 99

Chemical Property:

• PSA: 103.50000
• LogP: 5.35280

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,3R)-(+)-2,3-BUTANEDIOL DI-P-TOSYLATE, 99

There total 5 articles about (2R,3R)-(+)-2,3-BUTANEDIOL DI-P-TOSYLATE, 99 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(R,R)-2,3-butandiol (24347-58-8) + p-toluenesulfonyl chloride (98-59-9) → -2,3-butandiol di-(4-methylbenzolsulfonat) (64896-27-1)

Guidance literature:

With pyridine; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201504483

Reference yield: 55.0%

(R,R)-2,3-butandiol (24347-58-8) + p-toluenesulfonyl chloride (98-59-9) → (+/-)-2,3-butanediol di-p-tosylate (49662-27-3,64896-27-1,74839-83-1,90026-01-0,90026-02-1) + (-)-(1R,2R)-2-hydroxy-1-methylpropyl p-toluenesulfonate

Guidance literature:

In pyridine; for 23h; Ambient temperature;

DOI:10.1002/hlca.19840670324

Reference yield:

d,l-2,3-butanediol (6982-25-8) + p-toluenesulfonyl chloride (98-59-9) → (+/-)-2,3-butanediol di-p-tosylate (49662-27-3,64896-27-1,74839-83-1,90026-01-0,90026-02-1)

Guidance literature:

With pyridine;

DOI:10.1021/ja01213a017

upstream raw materials:

(R,R)-2,3-butandiol

p-toluenesulfonyl chloride

<2R-(2α(2R*,3R*),3aα,4α,7α,7aα)>-3-<(Octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>-2-butanol

2,3-dihydroxybutane

Downstream raw materials:

(2S,3S)-bis(2-iodo-3-nitrophenoxyl)butane

(S,S)-(4-methoxyphenyl)2P-CH(methyl)CH(methyl)-P(4-methoxyphenyl)2

(2S,3S)-2,3-bis(diphenylphosphino)butane

Refernces

• 1、 Gao, Xiang,Wu, Bo,Huang, Wen-Xue,Chen, Mu-Wang,Zhou, Yong-Gui. "Enantioselective Palladium-Catalyzed C-H Functionalization of Indoles Using an Axially Chiral 2,2′-Bipyridine Ligand". supporting information. p. 11956 - 11960. Retrieved 2015/10/12.
• 2、 -. "Highly Active and Selective Ethylene Oligomerization Catalyst and Method of Preparing Hexene or Octene Using the Same". Page/Page column 6-7. . Retrieved 2012/06/01.