7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Base Information

Chemical Name:7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester
CAS No.:1204005-96-8
Molecular Formula:C₂₀H₃₀N₂O₅
Molecular Weight:378.469
Hs Code.:

Synonyms:7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Suppliers and Price of 7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

There total 3 articles about 7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3946-32-5
suberic acid monomethyl ester

: 68621-88-5
(3-aminophenyl)carbamic acid tert-butyl ester

: 1204005-96-8
7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Guidance literature:: suberic acid monomethyl ester; With 4-methyl-morpholine; chloroformic acid ethyl ester; In dichloromethane; at 0 ℃; for 0.25h;

(3-aminophenyl)carbamic acid tert-butyl ester; In dichloromethane; at 20 ℃;
DOI:10.1016/j.ejmech.2018.09.024

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1204005-96-8
7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloromethane / 18 h / 20 °C / Cooling with ice

2.1: chloroformic acid ethyl ester; 4-methyl-morpholine / dichloromethane / 0.25 h / 0 °C

2.2: 20 °C

With 4-methyl-morpholine; chloroformic acid ethyl ester; In dichloromethane;
DOI:10.1016/j.ejmech.2018.09.024

Reference yield:

: 99-09-2
3-nitro-aniline

: 1204005-96-8
7-(3-(tert-butoxycarbonylamino)phenylcarbamoyl)heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; dmap / dichloromethane / 3 h / 20 °C

2: iron; ammonium chloride / isopropyl alcohol; water / 2 h / Reflux

3: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C

With dmap; iron; ammonium chloride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; In dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1016/j.ejmech.2019.111725