1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

Base Information

Chemical Name:1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea
CAS No.:641611-53-2
Molecular Formula:C₂₆H₃₄N₂O₅S
Molecular Weight:486.632
Hs Code.:

Synonyms:1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

Suppliers and Price of 1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

There total 1 articles about 1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1700-31-8
3-benzyloxybenzyl bromide

: 107819-90-9
1,3-bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea

: 641611-53-2
1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

Guidance literature:: 1,3-bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea; With sodium hydride; In N,N-dimethyl-formamide; for 1h; cooling;

3-benzyloxybenzyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/jm0309203

Reference yield: 30.0%

: 126898-43-9
5'-amino-17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan

: 641611-53-2
1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

: 641611-54-3
17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-5'-bis-tert-butoxycarbonyl-(N'-3-benzyloxybenzyl)guanidinyl-3,14-dihydroxyindolo[2',3':6,7]morphinan

Guidance literature:: With triethylamine; mercury dichloride; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1021/jm0309203

Reference yield:

: 641611-53-2
1,3-bis-tert-butoxycarbonyl-1-(3'-benzyloxybenzyl)-2-methyl-2-thiopseudourea

: 17-cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-5'-bis-tert-butoxycarbonyl-(N'-3-hydroxybenzyl)guanidinyl-3,14-dihydroxyindolo[2',3':6,7]morphinan tri-hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / HgCl₂; Et₃N / dimethylformamide / 50 °C

2: 98 percent / aq. HCl / methanol / 75 °C

With hydrogenchloride; triethylamine; mercury dichloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm0309203