Technology Process of C35H47N7O9
There total 8 articles about C35H47N7O9 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer;
In
tetrahydrofuran; methanol;
at 50 ℃;
for 15h;
regioselective reaction;
Inert atmosphere;
DOI:10.1021/ol201184b
- Guidance literature:
-
Multi-step reaction with 7 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: iodine; silver trifluoroacetate / chloroform / 15 h / 20 °C
3: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 15 h / 20 °C
4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
5: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 20 °C
6: tetrabutyl ammonium fluoride / tetrahydrofuran; methanol / 3 h / 20 °C
7: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / tetrahydrofuran; methanol / 15 h / 50 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; tetrabutyl ammonium fluoride; iodine; silver trifluoroacetate; potassium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
3: Sonogashira coupling;
DOI:10.1021/ol201184b
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran; methanol / 3 h / 20 °C
2: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / tetrahydrofuran; methanol / 15 h / 50 °C / Inert atmosphere
With
chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; methanol;
DOI:10.1021/ol201184b