tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Base Information

Chemical Name:tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate
CAS No.:317356-47-1
Molecular Formula:C₂₁H₂₃F₃N₂O₄
Molecular Weight:424.42
Hs Code.:

Synonyms:tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Suppliers and Price of tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

There total 5 articles about tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 181519-16-4
tert-butyl 4-amino-3-methoxyphenylacetate

: 2285-12-3
o-trifluoromethyl-phenylisocyanate

: 317356-47-1
tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Guidance literature:: With triethylamine; In tetrahydrofuran;

Reference yield:

: 181518-01-4
tert-butyl (3-methoxy-4-nitrophenyl)acetate

: 317356-47-1
tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / hydrogen; acetic acid / Pd/C / ethanol / 24 h / 20 °C

2: triethylamine / tetrahydrofuran / 12 h / 20 °C

With hydrogen; acetic acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmc.2006.12.006

Reference yield:

: 90323-26-5
2-diazo-1-(3-methoxy-4-nitro-phenyl)-ethanone

: 317356-47-1
tert-butyl 3-methoxy-4-[N'-(2-trifluoromethylphenyl)ureido]phenylacetate

Guidance literature:: Multi-step reaction with 3 steps

1: 17.4 g / triethylamine; PhCO₂Ag / toluene / 1 h / Heating

2: 89 percent / hydrogen; acetic acid / Pd/C / ethanol / 24 h / 20 °C

3: triethylamine / tetrahydrofuran / 12 h / 20 °C

With hydrogen; silver benzoate; acetic acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; toluene; 1: Arndt-Eistert reaction;
DOI:10.1016/j.bmc.2006.12.006