3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid

Base Information

Chemical Name:3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid
CAS No.:955372-91-5
Molecular Formula:C₁₈H₁₁ClFIN₂O₂
Molecular Weight:468.653
Hs Code.:

Synonyms:3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid

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Chemical Property of 3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid

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Technology Process of 3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid

There total 1 articles about 3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 955372-90-4
3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid methyl ester

: 955372-91-5
3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid

Guidance literature:: 3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid methyl ester; With methanol; sodium hydroxide; water; at 60 ℃;

With hydrogenchloride; In water;

Reference yield: 41.0%

: 955372-91-5
3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid

: 955372-92-6
3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid hydrazide

Guidance literature:: 3-(2-chloro-phenyl)-5-(2-fluoro-4-iodo-phenylamino)-isonicotinic acid; With 1,1'-carbonyldiimidazole; In dimethyl sulfoxide; at 60 ℃;

With hydrazine; In water; dimethyl sulfoxide; at 60 ℃; for 4h;