(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Base Information

Chemical Name:(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate
CAS No.:1337556-20-3
Molecular Formula:C₃₉H₄₅NO₅Si
Molecular Weight:635.875
Hs Code.:

Synonyms:(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Suppliers and Price of (E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

There total 4 articles about (E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl (Z)-2-[hydroxy(phenyl)methyl]-3-iodo-2-propenoate

: 1337556-20-3
(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: palladium diacetate; sodium carbonate / 1,2-dimethoxyethane; water / 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 1 h / 0 - 10 °C

2.2: 20 h / 20 °C / Saturated solution

3.1: dmap; triethylamine / dichloromethane / 23 h / 0 - 20 °C / Inert atmosphere

4.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 20 °C

With dmap; lithium aluminium tetrahydride; palladium diacetate; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; dichloromethane; water; 1.1: Suzuki coupling;
DOI:10.1021/jo201727g

Reference yield:

: C₁₆H₁₆O₂

: 1337556-20-3
(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane / 23 h / 0 - 20 °C / Inert atmosphere

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane;
DOI:10.1021/jo201727g

Reference yield:

: 210752-49-1
ethyl (2Z)-2-(1-hydroxy-1-phenylmethyl)-3-phenylacrylate

: 1337556-20-3
(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 1 h / 0 - 10 °C

1.2: 20 h / 20 °C / Saturated solution

2.1: dmap; triethylamine / dichloromethane / 23 h / 0 - 20 °C / Inert atmosphere

3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 h / 20 °C

With dmap; lithium aluminium tetrahydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jo201727g