3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

Base Information

Chemical Name:3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester
CAS No.:1222084-44-7
Molecular Formula:C₁₉H₂₈BrNO₄
Molecular Weight:414.34
Hs Code.:

Synonyms:3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

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Chemical Property of 3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

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Technology Process of 3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

There total 1 articles about 3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1222084-48-1
3-(4-methylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

: 1222084-44-7
3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In dichloromethane; at 50 ℃; for 2h;
DOI:10.1002/jlcr.1701

Reference yield: 65.0%

: 1222084-44-7
3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

: 1222084-49-2
3-(4-fluoromethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

Guidance literature:: With silver fluoride; In acetonitrile; at 65 ℃; for 3h;
DOI:10.1002/jlcr.1701

Reference yield:

: 1222084-44-7
3-(4-bromomethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

: 1222084-45-8
3-(4-[⁽¹⁸⁾F]fluoromethylphenyl)-2-L-tert-butoxycarbonylaminopropionic acid tert-butyl ester

Guidance literature:: With [¹⁸F]-potassium fluoride; potassium carbonate; [2.2.2]cryptande; In acetonitrile; at 120 ℃; for 0.0833333h; Inert atmosphere;
DOI:10.1002/jlcr.1701