Technology Process of (2E,7E)-1-(Benzyloxy)-2,7,9-decatriene
There total 11 articles about (2E,7E)-1-(Benzyloxy)-2,7,9-decatriene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
at -78 - 25 ℃;
DOI:10.1021/ja00241a059
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 100 percent / DMAP, Et3N / CH2Cl2 / 12 h
2: 92 percent / DIBAL-H / tetrahydrofuran; toluene / 3 h / 0 °C
3: 78 percent / NaH / dimethylformamide / 1.) 1 h, 2.) r.t., 12 h
4: 97 percent / p-TsOH / methanol / 12 h
5: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 30 min, 2.) -78 deg C to r.t., 45 min
6: tetrahydrofuran; hexamethylphosphoric acid triamide / 1.) -78 deg C, 5 min, 2.) -78 deg C to r.t., 8 h
With
dmap; oxalyl dichloride; sodium hydride; diisobutylaluminium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo00102a016
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 78 percent / NaH / dimethylformamide / 1.) 1 h, 2.) r.t., 12 h
2: 97 percent / p-TsOH / methanol / 12 h
3: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 30 min, 2.) -78 deg C to r.t., 45 min
4: tetrahydrofuran; hexamethylphosphoric acid triamide / 1.) -78 deg C, 5 min, 2.) -78 deg C to r.t., 8 h
With
oxalyl dichloride; sodium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; N,N-dimethyl-formamide;
DOI:10.1021/jo00102a016