benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside

Base Information

• Chemical Name: benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside
• CAS No.: 873797-10-5
• Molecular Formula: C₃₁H₃₅O₈P
• Molecular Weight: 566.588
• Mol file: 873797-10-5.mol

Synonyms:benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside

Chemical Property of benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside

There total 1 articles about benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

Dibenzyl N,N-diisopropylphosphoramidite (108549-23-1) + benzyl (Z)-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-hept-5-enofuranoside (105592-35-6) → benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside (873797-10-5)

Guidance literature:

Dibenzyl N,N-diisopropylphosphoramidite; benzyl (Z)-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-hept-5-enofuranoside; With 1H-tetrazole; In dichloromethane; acetonitrile; at 20 ℃; for 2h;

With tert.-butylhydroperoxide; In dichloromethane; acetonitrile; at 20 ℃; for 15h;

DOI:10.1016/j.carres.2005.10.003

Reference yield:

benzyl 7-O-[bis(benzyloxy)phosphoryl]-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-(Z)-hept-5-enofuranoside (873797-10-5) → benzyl 7-O-[bis(benzyloxy)phosphoryl]-2,3-O-isopropylidene-D-glycero-α-D-manno-heptofuranoside (873797-13-8) + benzyl 7-O-[bis(benzyloxy)phosphoryl]-2,3-O-isopropylidene-L-glycero-β-L-gulo-heptofuranoside

Guidance literature:

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In 1,4-dioxane; water; at 20 ℃; for 5h;

DOI:10.1016/j.carres.2005.10.003

upstream raw materials:

Dibenzyl N,N-diisopropylphosphoramidite

benzyl (Z)-5,6-dideoxy-2,3-O-isopropylidene-α-D-lyxo-hept-5-enofuranoside

Downstream raw materials:

benzyl 7-O-[bis(benzyloxy)phosphoryl]-2,3-O-isopropylidene-D-glycero-α-D-manno-heptofuranoside