2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone

Base Information

• Chemical Name: 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone
• CAS No.: 767288-57-3
• Molecular Formula: C₂₁H₁₉BrN₂O₂S
• Molecular Weight: 443.364
• Mol file: 767288-57-3.mol

Synonyms:2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone

Chemical Property of 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone

There total 3 articles about 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(2-bromophenyl-4-methyl)phenylmethanone (69617-43-2) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone (767288-57-3)

Guidance literature:

With acetyl chloride; In ethanol; for 13h; Heating;

DOI:10.1016/j.tet.2007.01.010

Reference yield:

4-methyl-2-bromobenzoyl chloride (53456-09-0) → 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone (767288-57-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.58 g / aluminum chloride / 6 h / Heating

2: 80 percent / acetyl chloride / ethanol / 13 h / Heating

With aluminium trichloride; acetyl chloride; In ethanol;

DOI:10.1016/j.tet.2007.01.010

Reference yield:

2-bromo-4-methylbenzoic acid (7697-27-0) → 2-bromo-4-methylbenzophenone 4-methylphenylsulfonylhydrazone (767288-57-3)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / CHCl₃ / 3 h / Heating

2: 0.58 g / aluminum chloride / 6 h / Heating

3: 80 percent / acetyl chloride / ethanol / 13 h / Heating

With aluminium trichloride; thionyl chloride; acetyl chloride; In ethanol; chloroform;

DOI:10.1016/j.tet.2007.01.010

upstream raw materials:

(2-bromophenyl-4-methyl)phenylmethanone

toluene-4-sulfonic acid hydrazide

4-methyl-2-bromobenzoyl chloride

2-bromo-4-methylbenzoic acid