Technology Process of 1,2-bis(2-(4-chlorophenyl)imidazo[2,1-b][1,3]selenazol-3-yl)diselenide
There total 2 articles about 1,2-bis(2-(4-chlorophenyl)imidazo[2,1-b][1,3]selenazol-3-yl)diselenide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-((4-chlorophenyl)ethynyl)-1H-imidazole;
With
n-butyllithium;
In
tetrahydrofuran; hexane; water;
at -78 ℃;
for 0.5h;
Inert atmosphere;
With
selenium;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
Inert atmosphere;
With
ammonium chloride;
In
tetrahydrofuran; hexane; water;
for 2h;
Air;
Inert atmosphere;
DOI:10.1002/adsc.201200075
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: copper(l) iodide; 2-acetylcyclohexanone; caesium carbonate / 1,4-dioxane / 18 h / 50 °C / Reflux; Inert atmosphere; Molecular sieve
2.1: n-butyllithium / tetrahydrofuran; hexane; water / 0.5 h / -78 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
2.3: 2 h / Air; Inert atmosphere
With
copper(l) iodide; n-butyllithium; 2-acetylcyclohexanone; caesium carbonate;
In
tetrahydrofuran; 1,4-dioxane; hexane; water;
DOI:10.1002/adsc.201200075
