toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester

Base Information

• Chemical Name: toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester
• CAS No.: 753459-20-0
• Molecular Formula: C₁₆H₂₄O₅S
• Molecular Weight: 328.43
• Mol file: 753459-20-0.mol

Synonyms:toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester

Chemical Property of toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester

There total 2 articles about toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

p-toluenesulfonyl chloride (98-59-9) + 2-(2-(pent-4-enyloxy)ethoxy)ethanol (753459-19-7) → toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester (753459-20-0)

Guidance literature:

With dmap; triethylamine; In dichloromethane;

DOI:10.1002/anie.200453963

Reference yield:

bromopentene (1119-51-3) → toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester (753459-20-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / aq. NaOH / 24 h / 80 °C

2: 87 percent / Et₃N; DMAP / CH₂Cl₂

With dmap; sodium hydroxide; triethylamine; In dichloromethane;

DOI:10.1002/anie.200453963

Reference yield: 53.0%

C14H17NO3S (1236827-29-4) + toluene-4-sulfonic acid 2-(2-pent-4-enyloxy-ethoxy)-ethyl ester (753459-20-0) → C23H33NO5S (1236827-68-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; Inert atmosphere;

DOI:10.1021/ol101233k

upstream raw materials:

p-toluenesulfonyl chloride

2-(2-(pent-4-enyloxy)ethoxy)ethanol

bromopentene

Downstream raw materials:

C₂₃H₃₃NO₅S