[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

Base Information

Chemical Name:[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester
CAS No.:1383718-08-8
Molecular Formula:C₂₆H₃₃N₅O₅
Molecular Weight:495.579
Hs Code.:

Synonyms:[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

Suppliers and Price of [3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Hazard Codes:

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Technology Process of [3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

There total 7 articles about [3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1383718-07-7
[3-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid tert-butyl ester

: 1383718-08-8
[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

Guidance literature:: With hydrogen; 10 wt% Pd(OH)2 on carbon; In ethanol; for 1h; under 760.051 Torr;

Reference yield:

: 1155371-80-4
(((4-isopropyl-1,3-phenylene)bis(oxy))bis(methylene))dibenzene

: 1383718-08-8
[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: nitric acid; acetic acid / 0.67 h / 70 - 80 °C

2.1: hydrogenchloride; tin(ll) chloride / ethanol; water / 4 h / 80 °C

2.2: 0 °C

3.1: trimethylsilylazide; tert.-butylnitrite / acetonitrile / 13 h / 0 - 20 °C

4.1: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

5.1: hydrogen / 10 wt% Pd(OH)2 on carbon / ethanol / 1 h / 760.05 Torr

With hydrogenchloride; tert.-butylnitrite; trimethylsilylazide; hydrogen; nitric acid; acetic acid; tin(ll) chloride; chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; 10 wt% Pd(OH)2 on carbon; In ethanol; water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1383717-81-4
1,5-bis-benzyloxy-2-isopropyl-4-azido-benzene

: 1383718-08-8
[3-(2,4-dihydroxy-5-isopropyl-phenyl)-3H-[1,2,3]triazol-4-yl]-(4-morpholin-4-yl-phenyl)-carbamic acid t-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: hydrogen / 10 wt% Pd(OH)2 on carbon / ethanol / 1 h / 760.05 Torr

With hydrogen; chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; 10 wt% Pd(OH)2 on carbon; In ethanol; N,N-dimethyl-formamide;