N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide

Base Information

• Chemical Name: N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide
• CAS No.: 683246-91-5
• Molecular Formula: C₁₈H₁₇NO₂S
• Molecular Weight: 311.404
• Mol file: 683246-91-5.mol

Synonyms:N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide

Chemical Property of N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide

There total 6 articles about N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2,2-dibromostyrene (7436-90-0) + 4-methyl-N-(2-propenyl)benzenesulfonamide (50487-71-3) → N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide (683246-91-5)

Guidance literature:

With copper(l) iodide; caesium carbonate; N,N`-dimethylethylenediamine; In N,N-dimethyl-formamide; at 60 ℃; for 48h; regioselective reaction; Inert atmosphere;

Reference yield: 77.0%

4-methyl-N-(2-propenyl)benzenesulfonamide (50487-71-3) + 1-Bromo-2-phenylacetylene (932-87-6) → N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide (683246-91-5)

Guidance literature:

With 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; potassium carbonate; In toluene; at 80 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.7b00076

Reference yield: 68.0%

4-methyl-N-(2-propenyl)benzenesulfonamide (50487-71-3) + potassium (2-phenylethynyl)trifluoroborate → N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide (683246-91-5)

Guidance literature:

With 1,2-dimethyl-1H-imidazole; copper(II) chloride dihydrate; oxygen; In dichloromethane; at 20 ℃; under 760.051 Torr; Molecular sieve;

DOI:10.1021/ol101322k

upstream raw materials:

4-methyl-N-(2-propenyl)benzenesulfonamide

1-Bromo-2-phenylacetylene

2,2-dibromostyrene

phenylacetylene

Downstream raw materials:

2-ethyl-2-phenyl-4-pentenenitrile

2,2-diphenyl-pent-4-enenitrile

(E)-2-phenyl-1-[(2-propenyl)(p-tolylsulfonyl)amino]ethenyl diphenyldithiophosphinate

N-[(Z)-2-phenyl-1-hexenyl]-N-2-propenyl-p-toluenesulfonamide