Philanthotoxin 343 tris(trifluoroacetate) salt

Base Information

• Chemical Name: Philanthotoxin 343 tris(trifluoroacetate) salt
• CAS No.: 144117-44-2
• Molecular Formula: 3C₂HF₃O₂*C₂₃H₄₁N₅O₃
• Molecular Weight: 777.682
• Mol file: 144117-44-2.mol

Synonyms:Philanthotoxin 343 tris(trifluoroacetate) salt

Chemical Property of Philanthotoxin 343 tris(trifluoroacetate) salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Philanthotoxin 343 tris(trifluoroacetate) salt

There total 12 articles about Philanthotoxin 343 tris(trifluoroacetate) salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trifluoroacetic acid (76-05-1) + (3-tert-butoxycarbonylamino-propyl)-[4-(tert-butoxycarbonyl-{3-[3-(4-tert-butoxy-phenyl)-2-butyrylamino-propionylamino]-propyl}-amino)-butyl]-carbamic acid tert-butyl ester (557792-65-1) → Philanthotoxin 343 tris(trifluoroacetate) salt (144117-44-2)

Guidance literature:

In dichloromethane; at 20 ℃; for 2.5h;

DOI:10.1016/S0223-5234(02)00003-X

Reference yield: 59.0%

Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) + trifluoroacetic acid (76-05-1) + di-tert-butyl butane-1,4-diylbis((3-aminopropyl)carbamate) (177213-61-5) + butyric acid (107-92-6) → Philanthotoxin 343 tris(trifluoroacetate) salt (144117-44-2)

Guidance literature:

Multistep reaction.;

DOI:10.1021/jm000220n

Reference yield:

C46H63N5O3 + trifluoroacetic acid (76-05-1) → Philanthotoxin 343 tris(trifluoroacetate) salt (144117-44-2)

Guidance literature:

With thiophenol; In dichloromethane; at 25 ℃; for 0.5h;

DOI:10.3390/molecules27020447

upstream raw materials:

Fmoc-Tyr(tBu)-OH

trifluoroacetic acid

di-tert-butyl butane-1,4-diylbis((3-aminopropyl)carbamate)

butyric acid

Downstream raw materials:

dichloro-PhTX-343-(TFA)3

dibromo-PhTX-343-(TFA)3

3-Nitro-PhTX-343-(TFA)3