tert-butyldiphenylsilyl 5-hydroxyhexyl ether

Base Information

• Chemical Name: tert-butyldiphenylsilyl 5-hydroxyhexyl ether
• CAS No.: 121671-80-5
• Molecular Formula: C₂₂H₃₂O₂Si
• Molecular Weight: 356.58
• Mol file: 121671-80-5.mol

Synonyms:tert-butyldiphenylsilyl 5-hydroxyhexyl ether

Chemical Property of tert-butyldiphenylsilyl 5-hydroxyhexyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tert-butyldiphenylsilyl 5-hydroxyhexyl ether

There total 10 articles about tert-butyldiphenylsilyl 5-hydroxyhexyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(+/-)-6-[(tert-butyldiphenylsilyl)oxy]-1,2-epoxyhexane (103791-54-4) → tert-butyldiphenylsilyl 5-hydroxyhexyl ether (121671-80-5)

Guidance literature:

With lithium triethylborohydride; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1016/S0040-4020(00)00009-0

Reference yield: 92.0%

5-t-butyldimethylsilyloxy-1-t-butyldiphenylsilyloxyhexane (121671-73-6) → tert-butyldiphenylsilyl 5-hydroxyhexyl ether (121671-80-5)

Guidance literature:

With water; lithium chloride; In N,N-dimethyl-formamide; at 90 ℃; for 144h; sealed tube;

DOI:10.1016/S0040-4039(97)10479-8

Reference yield: 69.0%

1-t-butyldiphenylsilyloxy-5-trimethylsilyloxyhexane (158527-87-8) → tert-butyldiphenylsilyl 5-hydroxyhexyl ether (121671-80-5)

Guidance literature:

With water; aluminium; In hexane; for 0.00444444h; Ambient temperature;

DOI:10.1016/S0040-4020(01)85572-1

upstream raw materials:

5-t-butyldimethylsilyloxy-1-t-butyldiphenylsilyloxyhexane

hexane-1,5-diol

tert-butylchlorodiphenylsilane

1-t-butyldiphenylsilyloxy-5-trimethylsilyloxyhexane

Downstream raw materials:

6-(tert-butyldiphenylsilyloxy)hexan-2-one

6-(tert-butyldiphenylsilyloxy)-2-methylhexane-1,2-diol

2,2,5-trimethyl-5-[4-(tert-butyldiphenylsilyloxy)butyl]-1,3-dioxolane

tert-butyldiphenylsilyl 5-methyl-5-hexen-1-yl ether