2-Bromo-5-nitropyridin-4-amine

Base Information

Chemical Name:2-Bromo-5-nitropyridin-4-amine
CAS No.:84487-15-0
Molecular Formula:C5H4BrN3O2
Molecular Weight:218.01
Hs Code.:2933399090
European Community (EC) Number:858-135-3
DSSTox Substance ID:DTXSID40516054
Wikidata:Q72448698
Mol file:84487-15-0.mol

Synonyms:2-Bromo-5-nitropyridin-4-amine;84487-15-0;4-Amino-2-bromo-5-nitropyridine;MFCD11100588;2-bromo-5-nitro-4-pyridinamine;2-BROMO-5-NITRO-PYRIDIN-4-YLAMINE;SCHEMBL858456;2-bromo-5-nitro-4-pyridineamine;AMY3310;DTXSID40516054;KBAXIFACFUIWMK-UHFFFAOYSA-N;2-bromanyl-5-nitro-pyridin-4-amine;AKOS015966448;CS-W019727;PB12008;DS-16941;SY098019;FT-0740636;EN300-343827;A840813;J-508412

Suppliers and Price of 2-Bromo-5-nitropyridin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-bromo-5-nitropyridin-4-amine
100mg
$ 65.00

SynQuest Laboratories
4-Amino-2-bromo-5-nitropyridine
100 mg
$ 101.00

SynQuest Laboratories
4-Amino-2-bromo-5-nitropyridine
250 mg
$ 159.00

SynChem
2-Bromo-5-nitropyridin-4-amine 95+%
5 g
$ 1140.00

Matrix Scientific
4-Amino-2-bromo-5-nitropyridine 95+%
10g
$ 4536.00

Matrix Scientific
4-Amino-2-bromo-5-nitropyridine 95+%
5g
$ 3024.00

Matrix Scientific
4-Amino-2-bromo-5-nitropyridine 95+%
1g
$ 1019.00

Crysdot
2-Bromo-5-nitropyridin-4-amine 95%
1g
$ 294.00

Chemenu
2-bromo-5-nitropyridin-4-amine 95%
1g
$ 318.00

Ambeed
2-Bromo-5-nitropyridin-4-amine 95%
250mg
$ 125.00

Total 40 raw suppliers

Chemical Property of 2-Bromo-5-nitropyridin-4-amine

Chemical Property:

Vapor Pressure:1.72E-06mmHg at 25°C
Refractive Index:1.682
Boiling Point:396.3 °C at 760 mmHg
PKA:0.79±0.42(Predicted)
Flash Point:193.5 °C
PSA：84.73000
Density:1.929 g/cm³
LogP:2.43890
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:216.94869
Heavy Atom Count:11
Complexity:160

Purity/Quality:

99% ^*data from raw suppliers

2-bromo-5-nitropyridin-4-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CN=C1Br)[N+](=O)[O-])N

Technology Process of 2-Bromo-5-nitropyridin-4-amine

There total 3 articles about 2-Bromo-5-nitropyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 4487-57-4
2,4-dibromo-5-nitropyridine

: 84487-15-0
2-bromo-5-nitropyridin-4-amine

Guidance literature:: With ammonium hydroxide; In tetrahydrofuran; water; at 45 ℃; for 1h;
DOI:10.1021/ml500352s

Reference yield:

: 607373-82-0
2-hydroxy-4-methoxy-5-nitro pyridine

: 84487-15-0
2-bromo-5-nitropyridin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: phosphorus(V) oxybromide / acetonitrile / 16 h / Reflux

2: ammonium hydroxide / water; tetrahydrofuran / 1 h / 45 °C

With ammonium hydroxide; phosphorus(V) oxybromide; In tetrahydrofuran; water; acetonitrile;
DOI:10.1021/ml500352s

Reference yield:

: 31872-62-5
4-methoxy-3-nitro-pyridine

: 84487-15-0
2-bromo-5-nitropyridin-4-amine

Guidance literature:: Multi-step reaction with 3 steps

1: ammonia; potassium tert-butylate; tert.-butylhydroperoxide / tetrahydrofuran / 0.25 h / -78 - -33 °C

2: phosphorus(V) oxybromide / acetonitrile / 16 h / Reflux

3: ammonium hydroxide / water; tetrahydrofuran / 1 h / 45 °C

With tert.-butylhydroperoxide; ammonium hydroxide; potassium tert-butylate; ammonia; phosphorus(V) oxybromide; In tetrahydrofuran; water; acetonitrile;
DOI:10.1021/ml500352s