1-(2-fluorobenzyl)tetrahydrothiophenium bromide

Base Information

• Chemical Name: 1-(2-fluorobenzyl)tetrahydrothiophenium bromide
• CAS No.: 1392146-55-2
• Molecular Formula: Br*C₁₁H₁₄FS
• Molecular Weight: 277.201
• Mol file: 1392146-55-2.mol

Synonyms:1-(2-fluorobenzyl)tetrahydrothiophenium bromide

Chemical Property of 1-(2-fluorobenzyl)tetrahydrothiophenium bromide

Chemical Property:

Purity/Quality:

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Technology Process of 1-(2-fluorobenzyl)tetrahydrothiophenium bromide

There total 1 articles about 1-(2-fluorobenzyl)tetrahydrothiophenium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

thiophene (110-01-0) + o-fluorobenzyl bromide (446-48-0) → 1-(2-fluorobenzyl)tetrahydrothiophenium bromide (1392146-55-2)

Guidance literature:

for 17h;

Reference yield: 80.0%

1,1-Diphenylethylene (530-48-3) + 1-(2-fluorobenzyl)tetrahydrothiophenium bromide (1392146-55-2) → 3-(2-fluorophenyl)-1,1-diphenylpropene

Guidance literature:

With mer-tris((2-pyridinyl-κN)phenyl-κ2C)iridium(III); sodium carbonate; In 1-methyl-pyrrolidin-2-one; for 16h; Schlenk technique; Irradiation;

DOI:10.1002/asia.201801732

Reference yield: 56.0%

1-(2-fluorobenzyl)tetrahydrothiophenium bromide (1392146-55-2) + ethyl cinnamate (4192-77-2) → rac-(1S,2R,3R)-ethyl 2-(2-fluorophenyl)-3-phenylcyclopropanecarboxylate

Guidance literature:

With lithium hexamethyldisilazane; (1,4,7,10-tetraoxacyclododecane); In dichloromethane; at -78 - 20 ℃; for 16h;

upstream raw materials:

thiophene

o-fluorobenzyl bromide