CID 13621667

Base Information

Chemical Name:CID 13621667
CAS No.:102152-24-9
Molecular Formula:C₂₅H₃₃N₃O₅
Molecular Weight:455.554
Hs Code.:
DSSTox Substance ID:DTXSID101025202
Nikkaji Number:J1.550.941D

Synonyms:102152-24-9;DTXSID101025202;(2S)-1-[2-(3,4-Dimethoxyphenyl)ethylamino]-3-[4-[5-(2-methoxyethyl)-1H-imidazol-2-yl]phenoxy]propan-2-ol

Suppliers and Price of CID 13621667

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of CID 13621667

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:14
Exact Mass:455.24202116
Heavy Atom Count:33
Complexity:520

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCCC1=CN=C(N1)C2=CC=C(C=C2)OCC(CNCCC3=CC(=C(C=C3)OC)OC)O
Isomeric SMILES:COCCC1=CN=C(N1)C2=CC=C(C=C2)OC[C@H](CNCCC3=CC(=C(C=C3)OC)OC)O

Technology Process of CID 13621667

There total 5 articles about CID 13621667 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102151-60-0
2-<4-(benzyloxy)phenyl>-4-(2-chloroethyl)imidazole

: 102152-24-9
(S)-2-<4-<3-<<2-(3,4-dimethoxyphenyl)ethyl>amino>-2-hydroxypropoxy>phenyl>-4-(2-methoxymethyl)imidazole

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) Na / 1.) reflux, 2.) 15 h

2: 84 percent / H₂ / Pd/C / ethanol / 2585.7 Torr

3: 1.) NaH / 1.) Me₂SO, 60 deg C, 15 min, 2.) Me₂SO, 60 deg C, overnight

4: 10percent NaOH / ethanol / 2 h / Heating

With sodium hydroxide; hydrogen; sodium; sodium hydride; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00156a028

Reference yield:

: 102151-59-7
2-<4-(benzyloxy)phenyl>-4-(2-hydroxyethyl)imidazole

: 102152-24-9
(S)-2-<4-<3-<<2-(3,4-dimethoxyphenyl)ethyl>amino>-2-hydroxypropoxy>phenyl>-4-(2-methoxymethyl)imidazole

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / thionyl chloride / 15 h / Ambient temperature

2: 1.) Na / 1.) reflux, 2.) 15 h

3: 84 percent / H₂ / Pd/C / ethanol / 2585.7 Torr

4: 1.) NaH / 1.) Me₂SO, 60 deg C, 15 min, 2.) Me₂SO, 60 deg C, overnight

5: 10percent NaOH / ethanol / 2 h / Heating

With sodium hydroxide; thionyl chloride; hydrogen; sodium; sodium hydride; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00156a028

Reference yield:

: 102151-61-1
2-<4-(benzyloxy)phenyl>-4-(2-methoxyethyl)imidazole

: 102152-24-9
(S)-2-<4-<3-<<2-(3,4-dimethoxyphenyl)ethyl>amino>-2-hydroxypropoxy>phenyl>-4-(2-methoxymethyl)imidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / H₂ / Pd/C / ethanol / 2585.7 Torr

2: 1.) NaH / 1.) Me₂SO, 60 deg C, 15 min, 2.) Me₂SO, 60 deg C, overnight

3: 10percent NaOH / ethanol / 2 h / Heating

With sodium hydroxide; hydrogen; sodium hydride; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00156a028