(R)-N₅-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide

Base Information

• Chemical Name: (R)-N₅-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide
• CAS No.: 191869-48-4
• Molecular Formula: C₂₈H₃₃N₇O₄
• Molecular Weight: 531.615

Synonyms:(R)-N₅-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide

Chemical Property of (R)-N₅-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-N₅-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide

There total 4 articles about (R)-N₅-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(R)-N5-[amino(nitroimino)-methyl]-N-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]phenyl]methyl]-N2-(diphenylacetyl)-ornithinamide (191869-41-7) → (R)-N5-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N2-(diphenylacetyl)-ornithinamide (191869-48-4)

Guidance literature:

With trifluoroacetic acid;

Reference yield:

diphenylacetic acid chloride (1871-76-7) → (R)-N5-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N2-(diphenylacetyl)-ornithinamide (191869-48-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; sodium hydroxide / tetrahydrofuran; water; ethyl acetate

3: trifluoroacetic acid

With hydrogenchloride; sodium hydroxide; trifluoroacetic acid; In tetrahydrofuran; water; ethyl acetate;

Reference yield:

(R)-N5-[amino-(nitroimino)-methyl]-N2-(diphenylacetyl)ornithine (159013-58-8) → (R)-N5-[amino(nitroimino)methyl]-N-[[4-(aminomethyl)phenyl]methyl]-N2-(diphenylacetyl)-ornithinamide (191869-48-4)

Guidance literature:

Multi-step reaction with 2 steps

2: trifluoroacetic acid

With trifluoroacetic acid;

upstream raw materials:

(R)-N₅-[amino(nitroimino)-methyl]-N-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]phenyl]methyl]-N₂-(diphenylacetyl)-ornithinamide

diphenylacetic acid chloride

(R)-N₅-[amino-(nitroimino)-methyl]-N₂-(diphenylacetyl)ornithine

tert-butyl 4-(aminomethyl)benzylcarbamate

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