(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Base Information

Chemical Name:(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester
CAS No.:867155-89-3
Molecular Formula:C₄₆H₇₉N₃O₁₀
Molecular Weight:834.147
Hs Code.:

(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Synonyms:(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Suppliers and Price of (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

There total 5 articles about (S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 867155-79-1
(3S,4S,5R)-4-Methyl-octadecane-1,3,5-triol

: 867155-89-3
(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 57 percent / CSA / dimethylformamide / 0.5 h / 25 °C

2.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 1.5 h / 0 °C

2.2: 86 percent / 4-DMAP / tetrahydrofuran; toluene / 0 - 25 °C

3.1: H₂ / Pd/C-ethylenediamine complex / methanol / 0.5 h / 25 °C

4.1: 192 mg / HOBt; EDCI / dimethylformamide / 0.5 h / 25 °C

With 2,4,6-trichlorobenzoyl chloride; camphor-10-sulfonic acid; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; ethylenediamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo050628y

Reference yield:

: 867155-81-5
(2S,3R)-2-((S)-2,2-Dimethyl-[1,3]dioxan-4-yl)-hexadecan-3-ol

: 867155-89-3
(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 1.5 h / 0 °C

1.2: 86 percent / 4-DMAP / tetrahydrofuran; toluene / 0 - 25 °C

2.1: H₂ / Pd/C-ethylenediamine complex / methanol / 0.5 h / 25 °C

3.1: 192 mg / HOBt; EDCI / dimethylformamide / 0.5 h / 25 °C

With 2,4,6-trichlorobenzoyl chloride; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; ethylenediamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo050628y

Reference yield:

: 867155-85-9
(S)-3-Benzyloxy-2-benzyloxycarbonylamino-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

: 867155-89-3
(S)-3-Benzyloxy-2-[(2S,3R)-2-((S)-2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-3-hydroxy-butyrylamino]-propionic acid (R)-1-[(R)-1-((S)-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C-ethylenediamine complex / methanol / 0.5 h / 25 °C

2: 192 mg / HOBt; EDCI / dimethylformamide / 0.5 h / 25 °C

With hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; ethylenediamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo050628y