2-Bromonicotinamide

Base Information

Chemical Name:2-Bromonicotinamide
CAS No.:87674-18-8
Molecular Formula:C6H5BrN2O
Molecular Weight:201.023
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30355757
Wikidata:Q82134804
Mol file:87674-18-8.mol

Synonyms:2-bromonicotinamide;87674-18-8;2-bromopyridine-3-carboxamide;2-BROMO NICOTINAMIDE;Bromonicotinamide;bromo nicotinamide;bromo-nicotinamide;2-Bromonicotinamide, 99%;SCHEMBL1379678;DTXSID30355757;IHOOHSQJKUMHIG-UHFFFAOYSA-N;AMY26041;MFCD00234155;AKOS002664332;AS-41335;CS-0313392;FT-0611421;A842334;AC-907/25004499

Suppliers and Price of 2-Bromonicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromonicotinamide
100mg
$ 115.00

Matrix Scientific
2-Bromonicotinamide 95+%
10g
$ 928.00

Matrix Scientific
2-Bromonicotinamide 95+%
5g
$ 585.00

Matrix Scientific
2-Bromonicotinamide 95+%
1g
$ 200.00

Crysdot
2-BROMONICOTINAMIDE 97%
1g
$ 94.00

Crysdot
2-BROMONICOTINAMIDE 97%
5g
$ 282.00

Crysdot
2-BROMONICOTINAMIDE 97%
10g
$ 470.00

Crysdot
2-BROMONICOTINAMIDE 97%
25g
$ 707.00

Chemenu
2-Bromonicotinamide 97%
25g
$ 661.00

Chemenu
2-Bromonicotinamide 97%
10g
$ 439.00

Total 30 raw suppliers

Chemical Property of 2-Bromonicotinamide

Chemical Property:

Vapor Pressure:9.53E-05mmHg at 25°C
Refractive Index:1.613
Boiling Point:338.9 °C at 760 mmHg
Flash Point:158.8 °C
PSA：55.98000
Density:1.71 g/cm³
LogP:1.64330
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:199.95853
Heavy Atom Count:10
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

2-Bromonicotinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(N=C1)Br)C(=O)N

Technology Process of 2-Bromonicotinamide

There total 2 articles about 2-Bromonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 35905-85-2
2-bromonicotinic acid

: 87674-18-8
2-bromonicotinamide

Guidance literature:: 2-bromonicotinic acid; With thionyl chloride; for 7h; Reflux;

With ammonia; at 0 ℃;
DOI:10.1021/acs.joc.9b00452

Reference yield:

: 3430-17-9
2-bromo-3-picoline

: 87674-18-8
2-bromonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: KMnO₄; H₂O

2: SOCl₂ / Behandeln des Reaktionsprodukts mit wss. NH₃ in Dioxan oder in Benzol

With potassium permanganate; thionyl chloride; water;
DOI:10.1021/jo01156a002

Reference yield: 97.0%

: 87674-18-8
2-bromonicotinamide

: 874-60-2
4-methyl-benzoyl chloride

: sodium (2-bromonicotinoyl)(4-methylbenzoyl)amide

Guidance literature:: 2-bromonicotinamide; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h; Inert atmosphere;

4-methyl-benzoyl chloride; In tetrahydrofuran; mineral oil; at -78 - 20 ℃;
DOI:10.1002/ejoc.201500277