5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose

Base Information

• Chemical Name: 5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose
• CAS No.: 204396-77-0
• Molecular Formula: C₁₆H₂₂N₂O₅S
• Molecular Weight: 354.427
• Mol file: 204396-77-0.mol

Synonyms:5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose

Chemical Property of 5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose

There total 1 articles about 5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(-)-5-amino-5-deoxy-1,2-O-isopropylidene-β-L-idofuranose (14685-99-5) + phenyl isothiocyanate (103-72-0) → 5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose (204396-77-0)

Guidance literature:

With triethylamine; Ambient temperature;

Reference yield: 80.0%

acetic anhydride (108-24-7) + 5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose (204396-77-0) → 3,6-di-O-acetyl-5-(N'-acetyl-N'-phenylthioureido)-5-deoxy-1,2-O-isopropylidene-β-L-idofuranose

Guidance literature:

With pyridine; at 20 ℃; for 24h;

DOI:10.1016/S0957-4166(00)00054-9

Reference yield: 69.0%

5-deoxy-5-(N'-phenylthioureido)-1,2-O-isopropylidene-β-L-idofuranose (204396-77-0) → (1S,2R,3S,4R,5R)-2,3,4-trihydroxy-N-(N'-phenylthiocarbamoyl)-6-oxa-nor-tropane

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 0.333333h;

upstream raw materials:

(-)-5-amino-5-deoxy-1,2-O-isopropylidene-β-L-idofuranose

phenyl isothiocyanate