4-bromo-N,N-dicyclohexylbenzamide

Base Information

Chemical Name:4-bromo-N,N-dicyclohexylbenzamide
CAS No.:327058-58-2
Molecular Formula:C₁₉H₂₆BrNO
Molecular Weight:364.326
Hs Code.:
DSSTox Substance ID:DTXSID501300547
Mol file:327058-58-2.mol

Synonyms:4-bromo-N,N-dicyclohexylbenzamide;327058-58-2;starbld0007452;Oprea1_812130;DTXSID501300547;STK225348;AKOS003288470;NCGC00332128-01;AB01325956-02

Suppliers and Price of 4-bromo-N,N-dicyclohexylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-bromo-N,N-dicyclohexylbenzamide

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:363.11978
Heavy Atom Count:22
Complexity:334

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)N(C2CCCCC2)C(=O)C3=CC=C(C=C3)Br

Technology Process of 4-bromo-N,N-dicyclohexylbenzamide

There total 2 articles about 4-bromo-N,N-dicyclohexylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 586-76-5
4-Bromobenzoic acid

: 327058-58-2
4-bromo-N,N-dicyclohexylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; DMF / 2 h / Heating

2: Et₃N / CH₂Cl₂ / 2 h

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1016/S0968-0896(01)00293-0

Reference yield:

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 586-75-4
4-chlorobenzoyl chloride

: 327058-58-2
4-bromo-N,N-dicyclohexylbenzamide

Guidance literature:: With triethylamine; In dichloromethane; for 2h;
DOI:10.1016/S0968-0896(01)00293-0

Reference yield: 58.0%

: 99455-05-7
2-methoxy-6-bromoquinoline

: 327058-58-2
4-bromo-N,N-dicyclohexylbenzamide

: 327057-70-5
N,N-dicyclohexyl-4-(2-methoxy-quinolin-6-yl)-benzamide

Guidance literature:: 2-methoxy-6-bromoquinoline; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -75 ℃;

With zinc(II) chloride; In tetrahydrofuran; pentane; at -75 - 25 ℃;

4-bromo-N,N-dicyclohexylbenzamide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; pentane; Heating;
DOI:10.1016/S0223-5234(00)01167-3